Renal function, in nephrology, is an indication of the kidney's condition and its role in renal physiology.
Glomerular filtration rate (GFR) describes the flow rate of filtered fluid through the kidney.
Most doctors use the plasma concentrations of the waste substances of creatinine and urea (U), as well as electrolytes (E), to determine renal function.
These measures are adequate to determine whether a patient is suffering from kidney disease.
However, blood urea nitrogen (BUN) and creatinine will not be raised above the normal range until 60% of total kidney function is lost.
Hence, the more accurate Glomerular filtration rate or its approximation of the creatinine clearance is measured
whenever renal disease is suspected or careful dosing of nephrotoxic drugs is required.
https://en.wikipedia.org/wiki/Renal_function
Al
Glomerular filtration rate (GFR) describes the flow rate of filtered fluid through the kidney.
Most doctors use the plasma concentrations of the waste substances of creatinine and urea (U), as well as electrolytes (E), to determine renal function.
These measures are adequate to determine whether a patient is suffering from kidney disease.
However, blood urea nitrogen (BUN) and creatinine will not be raised above the normal range until 60% of total kidney function is lost.
Hence, the more accurate Glomerular filtration rate or its approximation of the creatinine clearance is measured
whenever renal disease is suspected or careful dosing of nephrotoxic drugs is required.
https://en.wikipedia.org/wiki/Renal_function
Al
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